Document Detail

Secondary airway lesions in laryngomalacia: a different perspective.
MedLine Citation:
PMID:  21493429     Owner:  NLM     Status:  In-Data-Review    
Objective. To document the prevalence of secondary airway lesions (SALs) among children with laryngomalacia (LM). Study Design. A cross-sectional observational study. Setting. Single practice in a tertiary care pediatric facility. Subjects and Methods. Patients diagnosed with LM were initially identified from a prospectively kept surgical database. Patients with cardiac/large-vessel malformations, prematurity, repeated or prolonged intubations, acute infections, or prior airway surgery were excluded. Only children who had a full examination of the airway were included. Other associated diagnoses along with demographics, surgical intervention, and type of LM were included. Results. Over an 8-year period, 1112 patients underwent laryngoscopy and bronchoscopy. A total of 108 consecutive cases were diagnosed with LM (78 primary diagnosis and 30 secondary diagnosis). After excluding 17 with disorders associated with large airway disease, 91 LM patients were included. The mean age was 553.23 days (ranging between 5 days and 15 years); 60 were boys and 31 were girls. The prevalence of SALs was 7.7% (95% confidence interval, 7.65-7.76; 7 children; 4 subglottic stenosis, 4 tracheomalacia, 1 bronchomalacia, and 1 choanal atresia). Fifty-nine patients underwent supraglottoplasties, while 1 patient had a tracheostomy. Conclusions. After accounting for conditions known to be associated with large airway lesions, the prevalence of SALs associated with laryngomalacia was much less than previously reported. The authors hypothesize that the upper-end figures are a reflection of highly select cohorts and the inclusion of patients with other pathology known to be associated with subglottic stenosis, tracheomalacia, and bronchomalacia and low thresholds for diagnosing mild subglottic stenosis.
Hani A Rifai; Marc Benoit; Hamdy El-Hakim
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Publication Detail:
Type:  Journal Article     Date:  2010-12-29
Journal Detail:
Title:  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery     Volume:  144     ISSN:  1097-6817     ISO Abbreviation:  Otolaryngol Head Neck Surg     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-04-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508176     Medline TA:  Otolaryngol Head Neck Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  268-73     Citation Subset:  IM    
Pediatric Otolaryngology, Divisions of Pediatric Surgery and Otolaryngology, Department of Surgery, The Stollery Children's Hospital & University of Alberta Hospitals, Edmonton, Alberta, Canada.
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