| Second-trimester multifetal pregnancy reduction facilitates prenatal diagnosis before the procedure. | |
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MedLine Citation:
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PMID: 10689003 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the pregnancy outcome of selective second-trimester multifetal pregnancy reduction (MFPR) compared to first-trimester MFPR. DESIGN: Cohort analysis. SETTING: In Vitro Fertilization Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. PATIENT(s): The study groups comprised 38 and 70 patients who underwent selective second-trimester MFPR (group 1) and first-trimester MFPR (group 2) at mean gestational ages of 19.7 +/- 3.3 weeks and 11.7 +/- 0.7 weeks, respectively. INTERVENTION(s): Ultrasonographically guided intracardiac injection of potassium chloride (KCl) solution. MAIN OUTCOME MEASURE(s): Pregnancy outcome and obstetric complications. RESULT(s): No statistically significant difference was found between group 1 and group 2 regarding mean gestational age at delivery (35.4 +/- 3.4 weeks and 35.9 +/- 3.1 weeks, respectively); mean birth weight (2,318.9 +/- 565.7 g and 2, 138.1 +/- 529.4 g); and the incidence of obstetric complications. These complications included pregnancy loss (5.2% and 15.7%), pregnancy-induced hypertension (0 and 10%), discordancy (12% and 18. 4%), intrauterine growth restriction (0 and 40%), and gestational diabetes (0% and 6%). However, the rate of all pregnancy complications was lower among second-trimester MFPR patients. CONCLUSION(s): Selective second-trimester MFPR is associated with favorable perinatal outcome and may facilitate detection of structural and chromosomal anomalies before the procedure and selective reduction of the affected fetus. |
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Authors:
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E Geva; G Fait; I Yovel; L Lerner-Geva; Y Yaron; Y Daniel; A Amit; J B Lessing |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 73 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 2000 Mar |
Date Detail:
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Created Date: 2000-03-23 Completed Date: 2000-03-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 505-8 Citation Subset: IM |
Affiliation:
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Lis Maternity Hospital, Tel Aviv Sourasky Medical Center; The Chaim Sheba Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel. gevae@obgyn.ucsf.edu |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Birth Weight Cohort Studies Diabetes, Gestational Female Fetal Death / epidemiology Humans Hypertension Pregnancy Pregnancy Complications, Cardiovascular Pregnancy Outcome Pregnancy Reduction, Multifetal* / statistics & numerical data Pregnancy Trimester, First Pregnancy Trimester, Second Pregnancy, Multiple* / statistics & numerical data Prenatal Diagnosis* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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