Document Detail


Second trimester maternal serum hCG level in an Asian population: normal reference values by ultrasound dating.
MedLine Citation:
PMID:  10902826     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To establish normative data of maternal serum chorionic gonadotropin (hCG) during the second trimester in an Asian population. METHODS: We measured the maternal serum hCG levels in 17,955 normal singleton pregnancies between 15 and 21 weeks of gestation. The gestation age was estimated by measurement of fetal biparietal distance (BPD) in all cases. Median values of hCG at various gestational weeks were calculated and the values of hCG were converted to multiple of median (MoM). The incidences of low MoM value and high MoM value were also calculated. RESULTS: The mean and median values of hCG were 57,153 mIU/ml and 50,120 mIU/ml, respectively, at 15 weeks of gestation and then decreased to 30,898 mIU/ml and 26,226 mIU/ml, respectively, at 21 weeks. We found 8.6% and 9.4% of normal singleton pregnancies have hCG MoM values >2.0 MoM and <0.5 MoM, respectively. CONCLUSIONS: Our report provides a normal reference data of second trimester maternal hCG levels by ultrasound dating in an Asian population.
Authors:
H J Jou; M K Shyu; J C Shih; M Y Chang; C C Lim; C Y Tzeng; S M Chen; F J Hsieh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of maternal-fetal medicine     Volume:  9     ISSN:  1057-0802     ISO Abbreviation:  J Matern Fetal Med     Publication Date:    2000 Mar-Apr
Date Detail:
Created Date:  2000-09-14     Completed Date:  2000-09-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9211288     Medline TA:  J Matern Fetal Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  118-21     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Taiwan Adventist Hospital, Taipei.
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MeSH Terms
Descriptor/Qualifier:
Chorionic Gonadotropin / blood*
Female
Gestational Age*
Humans
Pregnancy
Pregnancy Trimester, Second
Reference Values
Ultrasonography, Prenatal*
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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