| Second trimester amniotic fluid endothelin-1 concentrations and subsequent development of intrauterine growth restriction. | |
| | |
MedLine Citation:
|
PMID: 17123690 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The purpose of this prospective study was to record endothelin-1 (ET-1) concentrations in the second trimester amniotic fluid and compare these values in women who developed intrauterine growth restriction (IUGR) later in pregnancy with those with uneventful pregnancies. METHOD: Amniotic fluid was retrieved by amniocentesis from 125 women in the second trimester of pregnancy. The levels of ET1 were measured by a sensitive and specific radioimmunoassay. RESULTS: From the 125 women included in the study 12 had pregnancies that later developed IUGR and 88 had uneventful pregnancies. The ET1 concentration was significantly higher (P<0.005) in women who later developed IUGR than in normal pregnancy (106 pg/ml versus 64.7 pg/ml). CONCLUSION: The amniotic fluid concentration of ET1 is elevated by the second trimester in women who later develop IUGR. |
| | |
Authors:
|
Lavinia Margarit; Anthony N Griffiths; Vassilios Tsapanos; Sotiris Tsakas; Dimitios Gumenos; George Decavalas |
Publication Detail:
|
Type: Journal Article Date: 2006-11-22 |
Journal Detail:
|
Title: European journal of obstetrics, gynecology, and reproductive biology Volume: 134 ISSN: 0301-2115 ISO Abbreviation: Eur. J. Obstet. Gynecol. Reprod. Biol. Publication Date: 2007 Oct |
Date Detail:
|
Created Date: 2007-10-23 Completed Date: 2007-12-06 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0375672 Medline TA: Eur J Obstet Gynecol Reprod Biol Country: Ireland |
Other Details:
|
Languages: eng Pagination: 192-5 Citation Subset: IM |
Affiliation:
|
Department of Obstetrics and Gynaecology, University Hospital of Patras, Greece. laviniamarg@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Amniotic Fluid / chemistry* Biological Markers Case-Control Studies Endothelin-1 / analysis, metabolism* Female Fetal Growth Retardation / metabolism* Humans Pregnancy Pregnancy Trimester, Second Prospective Studies |
| Chemical | |
Reg. No./Substance:
|
0/Biological Markers; 0/Endothelin-1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Terlipressin as an adjunct vasopressor in refractory hypotension after tricyclic antidepressant into...
Next Document: Re-laparotomy after cesarean section.