| Second trimester amniocentesis in assisted conception versus spontaneously conceived twins. | |
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MedLine Citation:
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PMID: 18675413 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To compare the outcome of amniocentesis in twins conceived with assisted reproduction technology (ART) versus spontaneously conceived twins. DESIGN: Retrospective analysis of case records between 1993 and 2006. SETTING: University-affiliated tertiary center for fetal medicine. PATIENT(S): 167 ART twin pregnancies and 275 spontaneous twin pregnancies. INTERVENTION(S): Genetic amniocentesis. MAIN OUTCOME MEASURE(S): Comparison of pregnancy loss rate and perinatal outcome between the ART and spontaneous twin-pregnancy groups. RESULT(S): The fetal loss rate was similar between the two groups (4.2% vs. 4.0% in the ART twins and spontaneous twins, respectively), although the interval between amniocentesis to miscarriage was statistically significantly shorter in the ART twins than the spontaneous twins (6.2 and 20.1 days, respectively). In all cases, fetal loss refers to the loss of the entire pregnancy. The preterm delivery rate before 37 weeks was statistically significantly higher in the ART group (64.1%) compared with controls (49.5%). CONCLUSION(S): Amniocentesis in ART twins carries a fetal loss rate similar to spontaneous twins. However, ART twins have a statistically significantly increased risk of preterm delivery especially before 32 weeks' gestation. |
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Authors:
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George Daskalakis; Eleftherios Anastasakis; Nikolaos Papantoniou; Spyros Mesogitis; Aris Antsaklis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 91 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-01 Completed Date: 2009-07-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 2572-7 Citation Subset: IM |
Affiliation:
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First Department of Obstetrics and Gynecology, Alexandra Maternity Hospital, Athens University, Athens, Greece. gdaskalakis@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amniocentesis
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methods* Confidence Intervals Female Humans Infant, Newborn Intensive Care Units, Neonatal / statistics & numerical data Pregnancy Pregnancy Complications / epidemiology Pregnancy Trimester, Second* Reproductive Techniques, Assisted / statistics & numerical data* Retrospective Studies Risk Twins / physiology* |
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