| Second trimester abortion with ethacridine lactate plus carboprost--which is the best time to administer the carboprost? | |
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MedLine Citation:
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PMID: 3145677 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Extra-amniotic ethacridine lactate plus intramuscular prostaglandin has become a popular method for terminating second trimester pregnancies. In this study, intrauterine pressure was continuously monitored in order to objectively compare the efficacy of 3 different times of administration of Carboprost (15-methyl PGF2 alpha) - at 2 hours, 4 hours and 8 hours after the instillation of ethacridine lactate. The best results were obtained with the administration of Carboprost 8 hours after the instillation of the extra-amniotic ethacridine lactate. The synergistic effect of ethacridine lactate and Carboprost is optimal after this time. This is probably because the ethacridine lactate will have produced sufficient cervical ripening to ensure optimal efficacy of the prostaglandin-induced uterine contractions in expelling the products of conception. |
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Authors:
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A Malpani; A Malpani; U Krishna |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Advances in contraception : the official journal of the Society for the Advancement of Contraception Volume: 4 ISSN: 0267-4874 ISO Abbreviation: Adv Contracept Publication Date: 1988 Jun |
Date Detail:
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Created Date: 1989-02-10 Completed Date: 1989-02-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8607435 Medline TA: Adv Contracept Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 151-7 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, K.E.M. Hospital, Bombay, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents* Abortifacient Agents, Nonsteroidal* Abortion, Induced* Acridines* / analogs & derivatives Carboprost* Drug Administration Schedule Ethacridine* / analogs & derivatives Female Humans Pregnancy Pregnancy Trimester, Second Prostaglandins F, Synthetic* Uterine Contraction / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents; 0/Abortifacient Agents, Nonsteroidal; 0/Acridines; 0/Prostaglandins F, Synthetic; 35700-23-3/Carboprost; 442-16-0/Ethacridine |
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