Document Detail

Second to fourth digit length ratio (2D:4D) and adult sex hormone levels: new data and a meta-analytic review.
MedLine Citation:
PMID:  17400395     Owner:  NLM     Status:  MEDLINE    
The relative length of the second (index) to the fourth (ring) finger (2D:4D) is a putative negative correlate of prenatal testosterone (T) exposure. Therefore, 2D:4D (and to a lesser extent D(r-l), the difference between 2D:4D in the right hand and in the left hand) has often been used to study effects of prenatal androgenization on human behavior and cognition. However, evidence suggests that 2D:4D may also be related to levels of circulating sex hormones in adults. This would question the validity of 2D:4D as a means of studying the effects of prenatal sex hormones. Here we present new data from two non-clinical samples (64 women and 102 men) regarding the relationships of 2D:4D and D(r-l) with circulating sex hormone levels. We then present a meta-analytic review of all the present evidence regarding this issue. The results suggest that, in the normal population, 2D:4D and D(r-l) are not associated with adult sex hormone levels. The findings from this current study add to the growing body of evidence demonstrating that 2D:4D is a suitable tool to study the effects of prenatal androgenization on human behavior and cognition.
Johannes Hönekopp; Luise Bartholdt; Lothar Beier; Andreas Liebert
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Publication Detail:
Type:  Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't     Date:  2007-04-02
Journal Detail:
Title:  Psychoneuroendocrinology     Volume:  32     ISSN:  0306-4530     ISO Abbreviation:  Psychoneuroendocrinology     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-30     Completed Date:  2007-07-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7612148     Medline TA:  Psychoneuroendocrinology     Country:  England    
Other Details:
Languages:  eng     Pagination:  313-21     Citation Subset:  IM    
Technische Universität Chemnitz, Institut für Psychologie, Wilhelm-Raabe Str. 43, D-09120 Chemnitz, Germany.
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MeSH Terms
Fingers / anatomy & histology*
Gonadal Steroid Hormones / analysis*
Reg. No./Substance:
0/Gonadal Steroid Hormones

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