Document Detail

Second primary cancers of the head and neck following treatment of initial primary head and neck cancers.
MedLine Citation:
PMID:  3343165     Owner:  NLM     Status:  MEDLINE    
The risk of a second primary cancer arising in the head and neck, following surgical or radiation treatment of an initial primary cancer in the head and neck, was evaluated for 2,151 patients whose first cancers were diagnosed and treated at UCLA between 1955 and 1979. Based on follow-up data ranging from 5 to 30 years, the rate of development of second cancers of the head and neck was in excess of 2.5 per 1000 person-years at risk. There was no statistically significant difference in the frequency or post-treatment interval of second primary cancers related to the type of treatment of the first cancer, whether that was surgery, radiation therapy, or surgery plus radiation therapy.
R G Parker; J E Enstrom
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International journal of radiation oncology, biology, physics     Volume:  14     ISSN:  0360-3016     ISO Abbreviation:  Int. J. Radiat. Oncol. Biol. Phys.     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-03-29     Completed Date:  1988-03-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7603616     Medline TA:  Int J Radiat Oncol Biol Phys     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  561-4     Citation Subset:  IM    
Dept. of Radiation Oncology, University of California, Los Angeles 90024.
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MeSH Terms
Head and Neck Neoplasms / etiology,  radiotherapy,  surgery,  therapy*
Middle Aged
Neoplasms, Multiple Primary / etiology*
Neoplasms, Radiation-Induced*
Surgical Procedures, Operative / adverse effects*

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