| Second pregnancy outcomes following preeclampsia in a first pregnancy. | |
| | |
MedLine Citation:
|
PMID: 16036400 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: We compared second pregnancy outcomes among women with and without preeclampsia in their first pregnancies who all had second pregnancies without preeclampsia. METHODS: One hundred thirty women with and 6148 without preeclampsia in their first pregnancies, who all had nonpreeclamptic second pregnancies, were included. Outcomes, including delivery gestational age, birthweight, small-for-gestational-age (SGA), and preterm delivery were compared. RESULTS: Overall, second pregnancy outcomes were not different between women with and without preeclampsia in their first pregnancy. However, when women were stratified by gestational timing of preeclampsia, women with preeclampsia at < 34 weeks (N = 22) had smaller infants and delivered earlier in their second nonpreeclamptic pregnancy compared to women with later preeclampsia (N = 108) or no preeclampsia in the first pregnancy. Women with early preeclampsia also had an increased risk of prematurity (< 37 weeks) in second pregnancies that persisted after controlling for confounding factors [Odds ratio (OR = 3.2)]. DISCUSSION: Second, nonpreeclamptic pregnancy outcomes are different between women with previous early preeclampsia and controls but not between late preeclampsia and controls. These findings support other epidemiological data indicating differences between early and late onset preeclampsia as well as a potential relationship of preeclampsia and spontaneous preterm birth. |
| | |
Authors:
|
Kristine Y Lain; Marijane A Krohn; James M Roberts |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy Volume: 24 ISSN: 1064-1955 ISO Abbreviation: Hypertens Pregnancy Publication Date: 2005 |
Date Detail:
|
Created Date: 2005-07-22 Completed Date: 2005-09-01 Revised Date: 2009-05-12 |
Medline Journal Info:
|
Nlm Unique ID: 9421297 Medline TA: Hypertens Pregnancy Country: United States |
Other Details:
|
Languages: eng Pagination: 159-69 Citation Subset: IM |
Affiliation:
|
Magee-Womens Research Institute, Pittsburgh, PA 15213, USA. klain@mail.magee.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Female Gravidity* Humans Infant, Newborn Logistic Models Pre-Eclampsia / complications* Pregnancy Pregnancy Outcome* Premature Birth |
| Grant Support | |
ID/Acronym/Agency:
|
P01-HD 30367/HD/NICHD NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Oxidant-antioxidant system changes relative to placental-umbilical pathology in patients with preecl...
Next Document: Pulse wave reflection in currently and previously preeclamptic women.