| "Second generation" prostaglandins: midtrimester pregnancy termination by intramuscular injection of a 15-methyl analog of prostaglandin F2alpha. | |
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MedLine Citation:
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PMID: 1245238 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Eighty midtrimester gravid patients were treated with prostaglandin 15(S)-15-methyl Fa alpha by repeated intramuscular injections of 250 mug at 2-hour intervals for the elective termination of pregnancy. A success rate of 97.5% was achieved, with a mean initiation-to-abortion time of 17.2 +/- 1.0 hours. Gastrointestinal side effects were prominent but no serious complications occurred. Serial serum progesterone determinations and continuous intra-amniotic pressure recording were carried out in selected cases and correlated with abortifacient activity. This method of pregnancy termination appears particularly suitable for use in the early midtrimester of gestation. |
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Authors:
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J Robins; L I Mann |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 27 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1976 Jan |
Date Detail:
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Created Date: 1976-03-30 Completed Date: 1976-03-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 104-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Induced* Adolescent Adult Female Humans Injections, Intramuscular Pregnancy Pregnancy Trimester, Second Progesterone / blood Prostaglandins F / administration & dosage*, adverse effects Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Prostaglandins F; 57-83-0/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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