Document Detail

Second-generation antipsychotics and constipation: A review of the literature.
MedLine Citation:
PMID:  20542667     Owner:  NLM     Status:  In-Data-Review    
Antipsychotics are the cornerstone in the management of psychotic disorders and schizophrenia. They are effective agents but also have a wide range of side effects. In the recent literature constipation as possible side effect has received little attention. A review of the literature concerning constipation associated with antipsychotics was performed. Overall constipation is a rarely studied or reported side effect of antipsychotic medication. Nevertheless constipation is a common side effect. Antipsychotic agents differ in their liability to induce constipation. Constipation can be severe and can lead to serious consequences such as paralytic ileus, bowel occlusion and death. Active screening, monitoring and treatment are recommended. Further research on incidence, prevalence, underlying mechanisms and preventive measures is required.
M De Hert; H Hudyana; L Dockx; C Bernagie; K Sweers; J Tack; S Leucht; J Peuskens
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Publication Detail:
Type:  Journal Article     Date:  2010-06-09
Journal Detail:
Title:  European psychiatry : the journal of the Association of European Psychiatrists     Volume:  26     ISSN:  1778-3585     ISO Abbreviation:  Eur. Psychiatry     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111820     Medline TA:  Eur Psychiatry     Country:  France    
Other Details:
Languages:  eng     Pagination:  34-44     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Masson SAS. All rights reserved.
University Psychiatric Centre, Campus Kortenberg, Catholic University Louvain, Leuvensesteenweg 517, 3070 Kortenberg, Belgium.
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