Document Detail

Seborrhoeic dermatitis.
MedLine Citation:
PMID:  21418692     Owner:  NLM     Status:  In-Data-Review    
INTRODUCTION: Seborrhoeic dermatitis affects at least 10% of the population. Malassezia (Pityrosporum) ovale is thought to be the causative organism, and causes inflammation by still poorly defined mechanisms. Seborrhoeic dermatitis tends to relapse after treatment. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of topical treatments for seborrhoeic dermatitis of the scalp in adults? What are the effects of topical treatments for seborrhoeic dermatitis of the face and body in adults? We searched: Medline, Embase, The Cochrane Library, and other important databases up to April 2010 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
RESULTS: We found 12 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: bifonazole, emollients, ketoconazole, lithium succinate, selenium sulphide, tar shampoo, terbinafine, and topical corticosteroids (betamethasone valerate, clobetasol propionate, clobetasone butyrate, hydrocortisone, mometasone furoate).
Luigi Naldi
Publication Detail:
Type:  Journal Article     Date:  2010-12-07
Journal Detail:
Title:  Clinical evidence     Volume:  2010     ISSN:  1752-8526     ISO Abbreviation:  Clin Evid (Online)     Publication Date:  2010  
Date Detail:
Created Date:  2011-03-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101294314     Medline TA:  Clin Evid (Online)     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Centro Studi GISED, Bergamo, Italy.
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