| Seborrhoeic dermatitis: treatment with anti-mycotic agents. | |
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MedLine Citation:
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PMID: 8051320 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In order to elucidate the effectiveness of anti-mycotics in treating seborrhoeic dermatitis, an attempt was made to isolate Malassezia from seborrhoeic lesions of patients of seborrhoeic dermatitis. The results revealed that, in male patients, 46/49 cases were positive for Malassezia furfur on the face and 30/48 cases were positive for M. furfur on the scalp. In female patients, 7/13 cases were positive for M. furfur on the face, and 6/17 cases were positive for M. furfur on the scalp. Anti-mycotic agents were excellent in 50% and good in 31% of the spore-positive cases, yielding an overall efficacy rate of 81%. In contrast, the treatment of the face with vehicle alone showed only one excellent result out of 8 cases. Although clinical improvement was rapid on the side treated with a topical corticosteroid in the half-side-test, numerous fungal elements remained. While the improvement with anti-mycotic agents was slower than that with the corticosteroid, clinical improvement became evident by the third week of administration and fungal elements disappeared. |
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Authors:
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Y Sei; T Hamaguchi; J Ninomiya; A Nakabayashi; I Takiuchi |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of dermatology Volume: 21 ISSN: 0385-2407 ISO Abbreviation: J. Dermatol. Publication Date: 1994 May |
Date Detail:
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Created Date: 1994-09-06 Completed Date: 1994-09-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7600545 Medline TA: J Dermatol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 334-40 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Showa University Fujigaoka Hospital, Yokohama, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Antifungal Agents / therapeutic use* Child Child, Preschool Dermatitis, Seborrheic / drug therapy*, microbiology Dermatomycoses / drug therapy Female Humans Malassezia / isolation & purification Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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