Document Detail


Sebaceous carcinoma arising on actinic keratosis.
MedLine Citation:
PMID:  10882948     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report two cases of sebaceous carcinoma arising on actinic keratosis. The first patient, a 75-year-old female, had a granuloma pyogenicum-like tumor on her left temple, and the second patient, an 81-year-old female, developed a tumor with erythema on her left cheek. In both cases, histopathological examination revealed findings typical of sebaceous carcinoma in the center of the tumors, and in the periphery, actinic elastosis and intraepidermal proliferation of squamoid atypical cells without vacuolation was observed. Immunohistochemical examinations using six antibodies also revealed that neoplastic cells of both cases demonstrated sebaceous differentiation. These cases suggest that extraocular sebaceous carcinoma may arise from actinic keratosis.
Authors:
S Ansai; I Mihara
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of dermatology : EJD     Volume:  10     ISSN:  1167-1122     ISO Abbreviation:  Eur J Dermatol     Publication Date:    2000 Jul-Aug
Date Detail:
Created Date:  2000-10-03     Completed Date:  2000-10-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9206420     Medline TA:  Eur J Dermatol     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  385-8     Citation Subset:  IM    
Affiliation:
Division of Dermatology, Yamagata Prefectural Nihon-kai Hospital, Sakata, Yamagata 998-8501, Japan. shinchan@nihonkai.gr.jp
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma, Sebaceous / pathology*
Aged
Aged, 80 and over
Facial Dermatoses / pathology*
Female
Humans
Immunohistochemistry
Keratosis / pathology*
Precancerous Conditions / pathology*
Sebaceous Gland Neoplasms / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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