| Sebaceous adenomas in an MYH associated polyposis patient of Indian (Gujarati) origin. | |
| | |
MedLine Citation:
|
PMID: 17874208 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
MYH associated polyposis is an autosomal recessive polyposis syndrome with a high risk of large bowel cancer, caused by mutations in the DNA repair gene MYH. Founder mutations have been described in different ethnic groups. Muir Torre Syndrome is the association of internal malignancies with sebaceous gland tumours; Lynch Syndrome/Hereditary Non Polyposis Cancer is the best known cause. There has been a previous report of sebaceous gland tumours in an Italian patient with MYH associated polyposis. We describe a man of Indian (Gujarati) descent who has MYH associated polyposis and multiple sebaceous adenomas of the skin. |
| | |
Authors:
|
Vadakke Kanakath Ajith Kumar; June Anne Gold; Eleanor Mallon; Shyamala Thomas; Shirley V Hodgson |
Related Documents
:
|
19796978 - Tnf receptor-associated periodic syndrome (traps): a new cause of joint destruction? 9207788 - Alagille syndrome is caused by mutations in human jagged1, which encodes a ligand for n... 12832748 - Tnfrsf1a-associated periodic syndrome (traps), muckle-wells syndrome (mws) and renal am... 19206178 - A missense mutation, p.v132g, in the x-linked spermine synthase gene (sms) causes snyde... 18482768 - Methanol intoxication-induced nigrostriatal dysfunction detected using 6-[18f]fluoro-l-... 1727618 - The cause and pathogenesis of the eosinophilia-myalgia syndrome. |
Publication Detail:
|
Type: Case Reports; Journal Article Date: 2007-09-15 |
Journal Detail:
|
Title: Familial cancer Volume: 7 ISSN: 1389-9600 ISO Abbreviation: Fam. Cancer Publication Date: 2008 |
Date Detail:
|
Created Date: 2008-06-18 Completed Date: 2008-10-09 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100898211 Medline TA: Fam Cancer Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 187-9 Citation Subset: IM |
Affiliation:
|
North East Thames Regional Genetics Service, Great Ormond Street Hospital, London WC1N 3JH, UK. KumarA@gosh.nhs.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenoma
/
diagnosis,
genetics* Adenomatous Polyposis Coli / complications, diagnosis, genetics* DNA Glycosylases / genetics* Humans India Male Middle Aged Mutation Risk Factors Sebaceous Gland Neoplasms / diagnosis, etiology, genetics* |
| Chemical | |
Reg. No./Substance:
|
EC 3.2.2.-/DNA Glycosylases; EC 3.2.2.-/mutY adenine glycosylase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Responsiveness of the Adult Attention-Deficit/Hyperactivity Disorder Quality of Life Scale (AAQoL).
Next Document: Ethics consultation and autonomy.