| Seasonality of schizophrenia and stillbirths. | |
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MedLine Citation:
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PMID: 8235458 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A study of the birth pattern of 30,467 patients with schizophrenia and 428,406 stillbirths in New York State showed a significant winter-month excess in both schizophrenia births (p = 0.0000) and stillbirths (p = 0.0000). Excess births of individuals with schizophrenia in November and December provided additional evidence to refute the age-incidence explanation for the observed seasonality. Time series spectral analysis showed coherence in the pattern of schizophrenia births and stillbirths of 0.898 (p < 0.003) with schizophrenia births preceding stillbirths by 13 days. These results suggest that a common etiological seasonal factor affects a subgroup of births of individuals who later develop schizophrenia and a subgroup of stillbirths. Nutritional factors, temperature, and infectious agents known to cause both central nervous system disease and stillbirths are possible candidates. |
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Authors:
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E F Torrey; A E Bowler; R Rawlings; A Terrazas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Schizophrenia bulletin Volume: 19 ISSN: 0586-7614 ISO Abbreviation: Schizophr Bull Publication Date: 1993 |
Date Detail:
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Created Date: 1993-12-03 Completed Date: 1993-12-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0236760 Medline TA: Schizophr Bull Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 557-62 Citation Subset: IM |
Affiliation:
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Twin Study Unit, NIMH Neurosciences Ctr., St. Elizabeths Hospital, Washington, DC 20032. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Birth Rate Cross-Sectional Studies Female Fetal Death / epidemiology, etiology* Hospitalization / statistics & numerical data Humans Incidence Male Middle Aged New York / epidemiology Pregnancy Prenatal Exposure Delayed Effects* Risk Factors Schizophrenia / epidemiology, etiology* Schizophrenic Psychology* Seasons* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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