Document Detail

Seasonality of birth in schizophrenia: the effect of regional population density.
MedLine Citation:
PMID:  9061813     Owner:  NLM     Status:  MEDLINE    
It has been suggested that winter birth in urban areas may be associated with an increased risk of schizophrenia. Data on 4139 patients with a hospital diagnosis of schizophrenia were obtained from a survey of public departments of psychiatry in metropolitan France. Place of birth was classified according to the administrative subdivision of French territory into 95 'départements'. Density of population in the decade and in the département of birth was identified using successive census data. A 20% excess (OR, 1.20; 95% CI, 1.03-1.40; p = 0.02) of winter births (January-March) was found among patients born in highly densely populated areas (> 136 inhabitants/km2) compared to those born in other areas. These results suggest that seasonal early environmental risk factor(s) linked to schizophrenia predominantly operate in urban areas.
H Verdoux; N Takei; R Cassou de Saint-Mathurin; R M Murray; M L Bourgeois
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Schizophrenia research     Volume:  23     ISSN:  0920-9964     ISO Abbreviation:  Schizophr. Res.     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-05-30     Completed Date:  1997-05-30     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  8804207     Medline TA:  Schizophr Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  175-80     Citation Subset:  IM    
Department of Psychiatry, University Victor Segalen Bordeaux 2, Centre Carreire, France.
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MeSH Terms
Middle Aged
Risk Factors
Schizophrenia / diagnosis,  epidemiology*
Urban Population*

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