Document Detail


Seasonality of birth in epilepsy: a Danish study.
MedLine Citation:
PMID:  9858097     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: A recent British epidemiological study, having found that the seasonality of birth in a large epileptic sample was significantly different from that of the general population, has pointed to neurodevelopmental disruption as the likely mechanism to cause at least part of the epilepsies of unknown aetiology. The aim of this study is to replicate the British study using a large Danish sample. MATERIAL AND METHODS: The population studied is composed by all the 50,886 patients discharged from Danish Hospitals, with a diagnosis of epilepsy, in the period from 1977 to 1993. The seasonal pattern of birth in this sample has been compared, using regression methods, with all the live births in Denmark. RESULTS: The results were strikingly similar to the British study, with a deficit of epileptic births in September and an excess during the winter months. CONCLUSION: This study seems to confirm the seasonal presence in the environment of an aetiological factor(s) for epilepsy which acts in the perinatal period disrupting the neurodevelopment.
Authors:
M Procopio; P K Marriott
Related Documents :
16242917 - Season of birth is associated with anthropometric and neurocognitive outcomes during in...
21415047 - Season of birth and anorexia nervosa.
18833587 - Decline in sex ratio at birth after bam (kerman province, southern iran) earthquake.
669397 - A short term study on the growth of garden lizards in the laboratory.
7319787 - Syndrome of inappropriate antidiuretic hormone secretion in newborn infants with respir...
23467627 - Estimation of fluoride intake from milk-based infant formulas and baby foods.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  98     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-02-26     Completed Date:  1999-02-26     Revised Date:  2006-08-16    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  297-301     Citation Subset:  IM    
Affiliation:
The Princess Royal Hospital, Haywards Heath, West Sussex, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Denmark / epidemiology
Environment
Epilepsy / epidemiology,  etiology*
Female
Humans
Male
Middle Aged
Models, Statistical
Nervous System / growth & development
Poisson Distribution
Pregnancy
Prenatal Exposure Delayed Effects*
Risk Factors
Seasons*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The c-wave of the electroretinogram recorded under clinical conditions from rabbits.
Next Document:  Multiple sclerosis in North African migrants to France.