| Seasonality of birth in epilepsy: a Danish study. | |
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MedLine Citation:
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PMID: 9858097 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: A recent British epidemiological study, having found that the seasonality of birth in a large epileptic sample was significantly different from that of the general population, has pointed to neurodevelopmental disruption as the likely mechanism to cause at least part of the epilepsies of unknown aetiology. The aim of this study is to replicate the British study using a large Danish sample. MATERIAL AND METHODS: The population studied is composed by all the 50,886 patients discharged from Danish Hospitals, with a diagnosis of epilepsy, in the period from 1977 to 1993. The seasonal pattern of birth in this sample has been compared, using regression methods, with all the live births in Denmark. RESULTS: The results were strikingly similar to the British study, with a deficit of epileptic births in September and an excess during the winter months. CONCLUSION: This study seems to confirm the seasonal presence in the environment of an aetiological factor(s) for epilepsy which acts in the perinatal period disrupting the neurodevelopment. |
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Authors:
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M Procopio; P K Marriott |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta neurologica Scandinavica Volume: 98 ISSN: 0001-6314 ISO Abbreviation: Acta Neurol. Scand. Publication Date: 1998 Nov |
Date Detail:
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Created Date: 1999-02-26 Completed Date: 1999-02-26 Revised Date: 2006-08-16 |
Medline Journal Info:
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Nlm Unique ID: 0370336 Medline TA: Acta Neurol Scand Country: DENMARK |
Other Details:
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Languages: eng Pagination: 297-301 Citation Subset: IM |
Affiliation:
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The Princess Royal Hospital, Haywards Heath, West Sussex, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Denmark / epidemiology Environment Epilepsy / epidemiology, etiology* Female Humans Male Middle Aged Models, Statistical Nervous System / growth & development Poisson Distribution Pregnancy Prenatal Exposure Delayed Effects* Risk Factors Seasons* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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