| Seasonal variations in the onset and healing rates of venous leg ulcers. | |
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MedLine Citation:
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PMID: 20118343 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: As many vascular pathologies exhibit circannual fluctuation, the aim of this study was to assess the chronobiological features of venous ulcers. METHODS: Based on a retrospective survey of the case histories of 391 venous ulcer patients, the rates of ulcer onset and healing in each month were analysed statistically; a time series was constructed to evaluate the seasonality. RESULTS: There was a significantly higher frequency of ulcer onset during the warmer part of the year (April-October), and onset showed strong seasonality. Healing rates were also unequally and statistically significantly distributed throughout the year: ulcers that appeared or that were treated with specialized treatment in the winter or summer healed slower in comparison to ulcers that began in the spring or autumn. CONCLUSIONS: Venous ulcers exhibit circannual fluctuations in their onset and healing rates. Hypothetically, in addition to exacerbation of chronic venous insufficiency, seasonal variations in immune system activity might potentially be responsible for this phenomenon. |
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Authors:
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M Simka |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Phlebology / Venous Forum of the Royal Society of Medicine Volume: 25 ISSN: 1758-1125 ISO Abbreviation: Phlebology Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-01 Completed Date: 2010-04-15 Revised Date: 2010-12-10 |
Medline Journal Info:
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Nlm Unique ID: 9012921 Medline TA: Phlebology Country: England |
Other Details:
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Languages: eng Pagination: 29-34 Citation Subset: IM |
Affiliation:
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Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland. mariansimka@poczta.onet.pl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Chemotaxis, Leukocyte Female Hot Temperature Humans Ischemia / complications Leg / blood supply Male Middle Aged Models, Biological Poland / epidemiology Retrospective Studies Seasons* Varicose Ulcer / epidemiology*, immunology, physiopathology Wound Healing / physiology* |
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