Document Detail


Seasonal variation of morphine physical dependence.
MedLine Citation:
PMID:  7198708     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The characteristics of morphine physical dependence in ground squirrels (Citellus lateralis) were examined during each of the four annual seasons. The results showed that this rodent hibernator exhibits a strong and characteristic naloxone-precipitated abstinence syndrome during its non-hibernation state, irrespective of the season. Although qualitatively unchanged throughout the year, the abstinence syndrome showed clear quantitative seasonal differences. These differences were evident in terms of both the number of occurrences of particular signs and the percentage of the morphine-dependent population exhibiting them.
Authors:
A L Beckman; C Llados-Eckman; T L Stanton; M W Adler
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Life sciences     Volume:  30     ISSN:  0024-3205     ISO Abbreviation:  Life Sci.     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-03-26     Completed Date:  1982-03-26     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0375521     Medline TA:  Life Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  147-53     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Clocks
Female
Humans
Male
Models, Biological
Morphine Dependence / epidemiology*
Naloxone / pharmacology
Sciuridae
Seasons
Substance Withdrawal Syndrome
Grant Support
ID/Acronym/Agency:
DA-02254/DA/NIDA NIH HHS
Chemical
Reg. No./Substance:
465-65-6/Naloxone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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