Document Detail

Seasonal variation in sudden infant death syndrome and bronchiolitis--a common mechanism?
MedLine Citation:
PMID:  8756818     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to compare epidemiologic features of sudden infant death syndrome (SIDS) and bronchiolitis and to apply statistical examination in order to examine the hypothesis that similar mechanisms could be at work in both conditions. The setting was Scotland from 1982 through 1990. We compared 1,211 deaths from SIDS with 10,058 hospital admissions for bronchiolitis in infancy. The comparisons included age, sex ratio, and seasonality. The sex ratios were similar (SIDS [M:F]:1.61:1; bronchiolitis: 1.63:1), but age distribution was different (chi 2 = 104.6, p < 0.001). When monthly rates throughout the year were compared using correlation of residuals from average season variation and by autocorrelation of residual series, no significant relationships were found between the two conditions (r2 = 0.0004). Once the seasonal pattern common to both conditions was accounted for, SIDS was not autocorrelated between months whereas bronchiolitis exhibited a high level of autocorrelation indicating an epidemic pattern for the latter but not for the former. While a common seasonal variation may indicate some shared etiologic factors associated with winter season, the two conditions do not appear to be closely related. The hypothesis that a common host susceptibility is at work is not supported. Further investigations of seasonal influences are warranted.
R Gupta; P J Helms; I T Jolliffe; A S Douglas
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of respiratory and critical care medicine     Volume:  154     ISSN:  1073-449X     ISO Abbreviation:  Am. J. Respir. Crit. Care Med.     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-10-24     Completed Date:  1996-10-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9421642     Medline TA:  Am J Respir Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  431-5     Citation Subset:  AIM; IM    
University Department of Child Health, University of Aberdeen, Scotland, United Kingdom.
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MeSH Terms
Age Distribution
Bronchiolitis, Viral / epidemiology*
Infant, Newborn
Linear Models
Patient Admission / statistics & numerical data
Scotland / epidemiology
Sex Ratio
Sudden Infant Death / epidemiology*,  etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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