| Seasonal fluctuation in birthweight in schizophrenia. | |
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MedLine Citation:
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PMID: 12223246 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The birthweights of 450 schizophrenic patients born in 1971-1978 were compared with those of individually matched controls from the same birth cohort. Schizophrenics born in the second quarter of the year (April to June) had a significantly lower birthweight than their controls and this was not attributable to differences in the duration of gestation. Analogous proband/control differences were not found in 301 patients with affective psychoses, but there was a similar, much smaller, seasonal fluctuation in birthweight in the general population. These findings may be a clue both to the genesis of the "season of birth effect" and to the identity of the intrauterine influences contributing to the aetiology of schizophrenia. Folate deficiency may be implicated. |
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Authors:
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R E Kendell; J H Boyd; V L Grossmith; M Bain Bain |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Schizophrenia research Volume: 57 ISSN: 0920-9964 ISO Abbreviation: Schizophr. Res. Publication Date: 2002 Oct |
Date Detail:
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Created Date: 2002-09-11 Completed Date: 2002-11-08 Revised Date: 2010-09-02 |
Medline Journal Info:
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Nlm Unique ID: 8804207 Medline TA: Schizophr Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 157-64 Citation Subset: IM |
Affiliation:
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Department of Psychiatry and the Information and Statistics Division of the Scottish National Health Service, Edinburgh University, UK. randakendell@yahoo.c.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Birth Weight* Case-Control Studies Female Humans Infant, Newborn Linear Models Male Matched-Pair Analysis Multivariate Analysis Schizophrenia / epidemiology* Scotland / epidemiology Seasons* |
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