Document Detail


Seasonal fluctuation in birthweight in schizophrenia.
MedLine Citation:
PMID:  12223246     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The birthweights of 450 schizophrenic patients born in 1971-1978 were compared with those of individually matched controls from the same birth cohort. Schizophrenics born in the second quarter of the year (April to June) had a significantly lower birthweight than their controls and this was not attributable to differences in the duration of gestation. Analogous proband/control differences were not found in 301 patients with affective psychoses, but there was a similar, much smaller, seasonal fluctuation in birthweight in the general population. These findings may be a clue both to the genesis of the "season of birth effect" and to the identity of the intrauterine influences contributing to the aetiology of schizophrenia. Folate deficiency may be implicated.
Authors:
R E Kendell; J H Boyd; V L Grossmith; M Bain Bain
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Schizophrenia research     Volume:  57     ISSN:  0920-9964     ISO Abbreviation:  Schizophr. Res.     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-09-11     Completed Date:  2002-11-08     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  8804207     Medline TA:  Schizophr Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  157-64     Citation Subset:  IM    
Affiliation:
Department of Psychiatry and the Information and Statistics Division of the Scottish National Health Service, Edinburgh University, UK. randakendell@yahoo.c.uk
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MeSH Terms
Descriptor/Qualifier:
Adult
Birth Weight*
Case-Control Studies
Female
Humans
Infant, Newborn
Linear Models
Male
Matched-Pair Analysis
Multivariate Analysis
Schizophrenia / epidemiology*
Scotland / epidemiology
Seasons*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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