Document Detail


Seasonal changes in mite allergen (Der I and Der II) concentrations in Japanese homes.
MedLine Citation:
PMID:  8595537     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: There has been no report on seasonal changes in Der II allergen in floor and bedding dust. OBJECTIVE: The purpose of this study was to examine the extent of seasonal changes in Der I and Der II allergens in the floor and bedding dust found in houses. METHODS: We measured the absolute concentrations of mite allergens in dust collected monthly for 1 year from both the floors and bedding of eight houses in Tokyo. Dust samples were obtained from eight families without regard to their allergy histories. The concentrations of the Der p I, Der f I, and Der II allergens were measured by fluorometric sandwich ELISA. RESULTS: We found seasonal changes in the concentrations of these mite allergens. The highest concentrations of Der I (Der p I plus Der f I) and Der II (Der p II plus Der f II) were present from August to October, and the lowest ones from March to April. In floor dust, the mean highest concentrations of Der I and Der II (35.0 and 20.2 microgram of fine dust) were sevenfold and fivefold respectively, times the mean lowest concentrations. In bedding dust, the mean highest concentrations of Der I and Der II (51.3 and 29.6 microgram/g of fine dust) each were fourfold times the mean lowest concentrations. CONCLUSIONS: The patterns of seasonal changes in Der II in floor and bedding dust were similar to those of Der I.
Authors:
H Miyazawa; M Sakaguchi; S Inouye; K Ikeda; Y Honbo; H Yasueda; T Shida
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology     Volume:  76     ISSN:  1081-1206     ISO Abbreviation:  Ann. Allergy Asthma Immunol.     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1996-04-12     Completed Date:  1996-04-12     Revised Date:  2006-04-19    
Medline Journal Info:
Nlm Unique ID:  9503580     Medline TA:  Ann Allergy Asthma Immunol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  170-4     Citation Subset:  IM    
Affiliation:
Department of Public Health, Kyorin University, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Allergens / analysis*
Animals
Antigens, Dermatophagoides
Bedding and Linens / adverse effects
Dust / adverse effects*
Floors and Floorcoverings
Glycoproteins / analysis*
Humans
Mites / immunology*
Seasons*
Chemical
Reg. No./Substance:
0/Allergens; 0/Antigens, Dermatophagoides; 0/Dust; 0/Glycoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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