| Seasonal variation in serum lipid levels in Japanese workers. | |
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MedLine Citation:
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PMID: 20215703 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: Seasonal variation in serum lipid levels in the Japanese population remains unclear. The aim of this study was to determine whether a variation in lipid levels exists in Japanese workers. METHODS: We investigated 1,331 employees in our institution (1,192 men, 44+/-10 years; 139 women, 38+/-11 years) who underwent health checkups in both June (summer) and December (winter), 2008. RESULTS: Serum levels of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol, and triglyceride were significantly higher in winter than in summer (129.1+/-31.2 mg/dL versus 125.2+/-30.2 mg/dL, p<0.0001; 65.9+/-16.8 mg/dL versus 63.5+/-16.1 mg/dL, p<0.0001; 110.4+/-67.5 mg/dL versus 107.5+/-70.4 mg/dL, p<0.05; respectively), although the ratio of LDL to HDL cholesterol was comparable (2.11+/-0.81 in summer versus 2.12+/-0.81 in winter). The frequency of study subjects diagnosed with hypercholesterolemia, defined as LDL cholesterol > or = 140 mg/dL, was significantly higher in winter than in summer (34.5 % versus 30.9 %, p<0.0001). CONCLUSION: In Japanese workers, we demonstrated that there is a seasonal variation in serum lipid levels and the prevalence of hypercholesterolemia. This result indicates that we have to give careful consideration to the season of blood sampling in the clinical diagnosis of and management decisions for hypercholesterolemia. |
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Authors:
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Fumihiko Kamezaki; Shinjo Sonoda; Yusuke Tomotsune; Hiromi Yunaka; Yutaka Otsuji |
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Publication Detail:
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Type: Journal Article Date: 2010-03-10 |
Journal Detail:
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Title: Journal of atherosclerosis and thrombosis Volume: 17 ISSN: 1880-3873 ISO Abbreviation: J. Atheroscler. Thromb. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-05 Completed Date: 2010-10-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9506298 Medline TA: J Atheroscler Thromb Country: Japan |
Other Details:
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Languages: eng Pagination: 638-43 Citation Subset: IM |
Affiliation:
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Second Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Asian Continental Ancestry Group Cholesterol, HDL / blood Female Humans Hypercholesterolemia / blood Lipids / blood* Lipoproteins, LDL / blood Male Middle Aged Seasons* Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Lipids; 0/Lipoproteins, LDL; 0/Triglycerides |
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