Document Detail

Season of birth in siblings of patients with seasonal affective disorder. A test of the parental conception habits hypothesis.
MedLine Citation:
PMID:  17902009     Owner:  NLM     Status:  MEDLINE    
Recently we have published a report on seasonally varying birth rates in 553 patients with seasonal affective disorder (SAD). The present study is aimed to test the hypothesis of an idiosyncratic seasonal conception pattern of the parents of these patients to explain this phenomenon. We conducted a telephone interview with the patients to obtain information on the birth data of their siblings. Using the method of chart review to acquire information on the family history of our patients, we excluded those siblings with psychiatric disorders. We first compared the birth months and the quarters of birth of 435 healthy siblings with the general population. Secondly, we compared the birth distribution of the index SAD patients with that of their siblings. There was a significant deviation between the birth distribution of the siblings and the general population calculated on a monthly basis (p = 0.044). When comparing quarters we found less births than expected in the first (-14.1%) and fourth quarter of the year (-15.1%) and an excess of births in the second (+7.7%) and third quarter (+21.1%; p = 0.018). There were no significant differences between the group of SAD patients and their siblings regarding their birth patterns as calculated by months (p = 0.848) or quarters (p = 0.320). Our study provides support for the hypothesis of specific parental conception habits underlying the birth seasonality in SAD. Further research could be conducted in non-seasonal depression as there is still a lack of studies on seasonality of birth in affective disorders.
Edda Pjrek; Dietmar Winkler; Nicole Praschak-Rieder; Matthäus Willeit; Jürgen Stastny; Anastasios Konstantinidis; Siegfried Kasper
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European archives of psychiatry and clinical neuroscience     Volume:  257     ISSN:  0940-1334     ISO Abbreviation:  Eur Arch Psychiatry Clin Neurosci     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2008-03-24     Completed Date:  2008-05-02     Revised Date:  2009-05-11    
Medline Journal Info:
Nlm Unique ID:  9103030     Medline TA:  Eur Arch Psychiatry Clin Neurosci     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  378-82     Citation Subset:  IM    
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
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MeSH Terms
Austria / epidemiology
Birth Rate*
Chi-Square Distribution
Cohort Studies
Middle Aged
Psychiatric Status Rating Scales
Seasonal Affective Disorder / epidemiology*,  genetics

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