Document Detail


Searching for the mountains of the moon: genome scans for atherosclerosis.
MedLine Citation:
PMID:  11931713     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Several research groups have begun mounting large, ambitious family studies to map genes for atherosclerosis, heart disease, and their major risk factors using whole genome linkage and/or disequilibrium scans. Some of the problems, pitfalls, and challenges of this exciting effort are examined and illustrated with lessons from an earlier mapping problem.
Authors:
Michael A Province
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Current atherosclerosis reports     Volume:  4     ISSN:  1523-3804     ISO Abbreviation:  Curr Atheroscler Rep     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-04-04     Completed Date:  2003-06-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  100897685     Medline TA:  Curr Atheroscler Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  169-75     Citation Subset:  IM    
Affiliation:
Division of Biostatistics, Washington University School of Medicine, 660 South Euclid, Box 8067, St. Louis, MO 63110, USA. mike@wubios.wustl.edu
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MeSH Terms
Descriptor/Qualifier:
Arteriosclerosis / genetics*
Chromosome Mapping / methods*
Genetic Predisposition to Disease / genetics
Heart Diseases / genetics
Humans
Grant Support
ID/Acronym/Agency:
GM28719/GM/NIGMS NIH HHS; HL54473/HL/NHLBI NIH HHS; HL56567/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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