Document Detail

Search for association between MCV and miscarriage, reflecting ethanol consumption or otherwise.
MedLine Citation:
PMID:  2627238     Owner:  NLM     Status:  MEDLINE    
In 38 miscarrying women and 38 pair-matched controls, all studied retrospectively, the mean pair-difference in MCV is + 1.2 fl, P less than 0.05 (one-tailed). As ethanol elevates MCV, this might weakly support the suggested role of ethanol in some miscarriages, although folate/B12 deficiencies cannot be excluded. The paper demonstrates only the feasibility of a first step in defining the possible role of ethanol in some miscarriages. It identifies a difficulty encountered from earlier attendance in the miscarrying group so that a later study could circumvent it and perhaps lead to a case for funding of a prospective enquiry into the dose-response relations of any association that might exist.
M L Fernandez-Fontecha; J H Renwick
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Alcohol and alcoholism (Oxford, Oxfordshire)     Volume:  24     ISSN:  0735-0414     ISO Abbreviation:  Alcohol Alcohol.     Publication Date:  1989  
Date Detail:
Created Date:  1990-04-16     Completed Date:  1990-04-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8310684     Medline TA:  Alcohol Alcohol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  497-502     Citation Subset:  IM    
Department of Epidemiology and Population Sciences, London School of Hygiene and Tropical Medicine, U.K.
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MeSH Terms
Abortion, Spontaneous / blood*
Alcohol Drinking / physiology*
Alcoholism / blood
Case-Control Studies
Dose-Response Relationship, Drug
Erythrocyte Indices / physiology*
Gestational Age
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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