Document Detail

Scurvy in pediatric patients: a review of 28 cases.
MedLine Citation:
PMID:  14700174     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study the dietary factors, clinical findings, plasma vitamin C level and post-treatment outcome of scurvy in pediatric patients at Queen Sirikit National Institute of Child Health. STUDY DESIGN: A retrospective study. METHOD: The medical and radiographic records of pediatric patients, diagnosed with scurvy at Queen Sirikit National Institute of Child Health from 1995 to 2002 were reviewed. RESULTS: Twenty-eight pediatric patients were diagnosed with scurvy. Their ages ranged between 10 months-9 years 7 months (median age of 29 months). 93 per cent of the cases were between 1-4 years of age. All were fed with well-cooked foods and small amounts or no vegetables and fruits. Supplementation with ultra heat temperature (UHT) milk was found in 89 per cent, average 5.8 boxes/day and 14.3 months in duration. Eighty-six per cent of cases were misdiagnosed previously. Clinical manifestations involved limp or inability to walk (96%), tenderness of lower limbs (86%), bleeding per gum (36%), fever (18%), and petechial hemorrhage (3.6%). All cases had abnormal radiographic findings compatible with scurvy and 2 cases had epiphyseal separation. All had clinical improvement within the first week after vitamin C supplementation. CONCLUSION: Vitamin C deficiency was found in the children's intake of small amounts or no vegetables and fruits together with UHT-milk. Frequent manifestations were limping and inability to walk and pain in the lower limbs. Response to vitamin C treatment was dramatic.
Suntaree Ratanachu-Ek; Pisit Sukswai; Yongyot Jeerathanyasakun; Lawan Wongtapradit
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  86 Suppl 3     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-12-31     Completed Date:  2004-02-05     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  S734-40     Citation Subset:  IM    
Department of Pediatrics, Queen Sirikit National Institute of Child Health, Bangkok 10400, Thailand.
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MeSH Terms
Ascorbic Acid / therapeutic use
Child, Preschool
Retrospective Studies
Risk Factors
Scurvy / diagnosis*,  drug therapy,  epidemiology
Thailand / epidemiology
Reg. No./Substance:
50-81-7/Ascorbic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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