Document Detail


Scurvy in a Child With Autism: Magnetic Resonance Imaging and Pathological Findings.
MedLine Citation:
PMID:  22258350     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We present a case of scurvy in a 6-year-old boy with autism and an unbalanced diet. The patient was admitted with difficulties in walking. Magnetic resonance imaging findings of the thigh showed diffuse signal abnormality in the bone marrow, periosteum, and the femoral muscle. A biopsy specimen of the femur showed hematoma, proliferative fibroblasts, and few collagen fibers, which suggested a deficiency of vitamin C. Although recurrent periosteal hematoma may be suggestive of scurvy, this finding was subtle in the current case. It is important to be aware of this rare disease because it is easily cured with vitamin C supplementation.
Authors:
Tetsu Niwa; Noriko Aida; Yukichi Tanaka; Mio Tanaka; Masae Shiomi; Jiro Machida
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-16
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  -     ISSN:  1536-3678     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
*Departments of Radiology †Pathology ‡Hemato-oncology/Regeneration Medicine §Orthopedic Surgery, Kanagawa Children's Medical Center, Mutsukawa, Minami-ku, Yokohama, Japan.
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