Document Detail


Screening for transmission of hepatitis within a liver unit.
MedLine Citation:
PMID:  4501839     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Detailed screening of the patients and staff in a unit specializing in liver disease was carried out over a year to ascertain whether transmission of the serum hepatitis virus was occurring and whether the situation was comparable in any way to that found in a Renal Haemodialysis Unit. Of the 154 patients with liver disease tested on admission, 6% were found to have Australia antigen in the serum and throughout the year there were rarely less than two patients in the ward at any one time with positive serum. No instances of clinical hepatitis were detected in the other patients following their stay in the ward or in their attendant medical, nursing and lay staff. Six staff members were found to have Australia antigen in their serum. In four of these, all nurses, it was present in the first sample tested and so the infection may have been acquired earlier. Temporary elevations in both plasma bilirubin and serum aspartate aminotransferase levels were found in another five staff members whose serum was negative for Australia antigen and who clinically were well. In a further eight and apparently healthy staff members, an isolated but persistent elevation of the plasma bilirubin was noted. In both groups these changes could represent the spread of subclinical infectious hepatitis and it is recommended that in units dealing with ;liver patients' not only should considerable care be taken during diagnostic and therapeutic procedures but the medical and nursing staff should be screened at regular intervals.
Authors:
P Bentley; D Haynes; P Sharpstone; P E Taylor; A J Zuckerman; R Williams
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of hygiene     Volume:  70     ISSN:  0022-1724     ISO Abbreviation:  J Hyg (Lond)     Publication Date:  1972 Mar 
Date Detail:
Created Date:  1972-06-01     Completed Date:  1972-06-01     Revised Date:  2010-09-10    
Medline Journal Info:
Nlm Unique ID:  0375374     Medline TA:  J Hyg (Lond)     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  197-202     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aspartate Aminotransferases / blood
Bilirubin / blood
Cross Infection*
Hepatitis B / complications,  diagnosis*
Hospital Departments
Humans
Liver Diseases / complications*
Medical Staff, Hospital
Nursing Staff, Hospital
Chemical
Reg. No./Substance:
635-65-4/Bilirubin; EC 2.6.1.1/Aspartate Aminotransferases
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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