Document Detail


Screening test for anti-Helicobacter pylori activity of traditional Chinese herbal medicines.
MedLine Citation:
PMID:  21105198     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
AIM: To evaluate the anti-Helicobacter pylori (H. pylori) activity of 50 traditional Chinese herbal medicines in order to provide the primary evidence for their use in clinical practice.
METHODS: A susceptibility test of water extract from 50 selected traditional Chinese herbal medicines for in vitro H. pylori Sydney strain 1 was performed with broth dilution method. Anti-H. pylori activity of the selected Chinese herbal medicines was evaluated according to their minimum inhibitory concentration (MIC).
RESULTS: The water extract from Rhizoma Coptidis, Radix Scutellariae and Radix isatidis could significantly inhibit the H. pylori activity with their MIC less than 7.8 mg/mL, suggesting that traditional Chinese herbal medicines have anti-inflammatory and antibacterial effects and can thus be used in treatment of H. pylori infection.
CONCLUSION: Rhizoma Coptidis, Radix Scutellariae and Radix isatidis are the potential sources for the synthesis of new drugs against H. pylori.
Authors:
Feng Ma; Ye Chen; Jing Li; He-Ping Qing; Ji-De Wang; Ya-Li Zhang; Bei-Guo Long; Yang Bai
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  16     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  5629-34     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Tonghe Road 1838, Guangzhou 510515, Guangdong Province, China. baiyang1030@hotmail.com.
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