| Screening for mutations of the androgen receptor gene in patients with isolated cryptorchidism. | |
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MedLine Citation:
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PMID: 11591424 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the occurrence of mutations of androgen receptor (AR) gene in patients with isolated cryptorchidism. DESIGN: Controlled clinical study. SETTING: Yamagata University Hospital, Yamagata and Tokyo Electric Power Company Hospital, Tokyo, Japan. PATIENT(S): Patients with isolated cryptorchidism (n = 48) and a control group of men with normal phenotype (n = 20). INTERVENTION(S): Blood (lymphocyte DNA). MAIN OUTCOME MEASURE(S): Screening of the AR gene in exons 1-8 using single-strand conformational polymorphism analysis. RESULT(S): No abnormal band patterns were detected in patients with cryptorchidism or in control subjects within the eight exons of the AR gene. CONCLUSION(S): AR gene alterations appear to be an unlikely cause of isolated cryptorchidism. |
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Authors:
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Y Suzuki; I Sasagawa; J Ashida; T Nakada; K Muroya; T Ogata |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 76 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 2001 Oct |
Date Detail:
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Created Date: 2001-10-09 Completed Date: 2001-12-04 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 834-6 Citation Subset: IM |
Affiliation:
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Department of Urology, Yamagata University School of Medicine, Yamagata, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Child, Preschool Cryptorchidism / genetics* Exons / genetics Genetic Testing* Humans Infant Male Mutation* Polymorphism, Single-Stranded Conformational Receptors, Androgen / genetics* Reference Values |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Androgen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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