Document Detail


Screening of microalgae for species excreting norharmane, a manifold biologically active indole alkaloid.
MedLine Citation:
PMID:  16872816     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A screening of microalgae strains is described, with the objective to discover more species besides the known cyanobacterium Nodularia harveyana which excrete the manifold biologically active and co-mutagenic indole alkaloid norharmane (9H-pyrido(3,4-b)indole) into their environment. Seven more cyanobacterial species, Anabaena cylindrica, Anabaena inaequalis, Anabaenopsis siamensis, Chroococcus minutus, Nostoc carneum, Nostoc commune and Phormidium foveolarum, were newly discovered. The norharmane concentrations detected for cyanobacterial culture media varied in a species-dependent manner from less than 1 up to 525 microg l(-1). The risk for humans and livestock, resulting from the natural appearance of norharmane as an extracellular metabolite of various cyanobacteria, is discussed.
Authors:
Rainer-B Volk
Related Documents :
14715236 - Phylogeny of holoparasitic orobanche (orobanchaceae) inferred from nuclear its sequences.
17598746 - The geographical pattern of speciation and floral diversification in the neotropics: th...
6454996 - Enzymes for species identification in the simulium damnosum complex form west africa.
8723266 - Long-term (1980-94) population trends of pestiferous chironomidae (diptera) along a lak...
11137236 - Infant and adolescent hepatitis b immunization up to 1999: a global overview.
18576786 - Serological survey of toxoplasma gondii in wild waterfowl in chukotka, kamchatka, russi...
Publication Detail:
Type:  Journal Article     Date:  2006-07-26
Journal Detail:
Title:  Microbiological research     Volume:  163     ISSN:  0944-5013     ISO Abbreviation:  Microbiol. Res.     Publication Date:  2008  
Date Detail:
Created Date:  2008-04-14     Completed Date:  2008-07-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9437794     Medline TA:  Microbiol Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  307-13     Citation Subset:  IM    
Affiliation:
Department of Pharmaceutical Biology, University of Kiel, Pharmaceutical Institute, Kiel, Germany. volk@pharmazie.uni-kiel.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Chromatography, Thin Layer
Cyanobacteria / metabolism*
Harmine / analogs & derivatives*,  chemistry,  metabolism,  toxicity
Humans
Indole Alkaloids / metabolism*,  toxicity
Chemical
Reg. No./Substance:
0/Indole Alkaloids; 244-63-3/norharman; 442-51-3/Harmine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Detection of antimicrobial activities and bacteriocin structural genes in faecal enterococci of wild...
Next Document:  Neem (Azadirachta indica a. Juss) components: candidates for the control of Crinipellis perniciosa a...