Document Detail

Screening for hyperglycaemia in pregnancy: Consensus and controversy.
MedLine Citation:
PMID:  20832736     Owner:  NLM     Status:  MEDLINE    
Policy decisions on whether to implement screening programmes depend on whether the proposed programmes meet a set of criteria laid down by the World Health Organization. Screening for hyperglycaemia in pregnancy (HGP) does not meet all the criteria. However the case for screening has been strengthened by a number of recent developments, including: rising prevalence of HGP because of increasing maternal age and BMI; the results of the Hyperglycaemia and Adverse Pregnancy Outcomes study, showing that adverse effects of HGP are seen over a wider range of plasma glucose levels than previously thought; two large trials which showed the benefits of treating lesser degrees of HGP; trials showing that metformin and glibenclamide were effective and safe alternatives to immediate insulin in those without good control on lifestyle measures alone. However uncertainties remain around the threshold for treatment, and on the best screening strategy.
Norman Waugh; Donald Pearson; Pamela Royle
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Best practice & research. Clinical endocrinology & metabolism     Volume:  24     ISSN:  1878-1594     ISO Abbreviation:  Best Pract. Res. Clin. Endocrinol. Metab.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-09-13     Completed Date:  2011-01-07     Revised Date:  2012-11-07    
Medline Journal Info:
Nlm Unique ID:  101120682     Medline TA:  Best Pract Res Clin Endocrinol Metab     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  553-71     Citation Subset:  IM    
Copyright Information:
2010. Published by Elsevier Ltd. All rights reserved.
Department of Public Health Medical School Buildings, Foresterhill, Aberdeen, UK.
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MeSH Terms
Body Mass Index
Diabetes, Gestational / diagnosis*,  epidemiology
Glucose Tolerance Test / methods
Great Britain / epidemiology
Hyperglycemia / diagnosis*
Mass Screening / economics,  standards*
Maternal Age
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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