Document Detail


Screening of forme fruste keratoconus with the ocular response analyzer.
MedLine Citation:
PMID:  19907025     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate the performance of the Ocular Response Analyzer (ORA) in the screening of forme fruste keratoconus (FFKc). METHODS: A retrospective comparative study was conducted involving 180 eyes. ORA preoperative data were analyzed for 125 normal control eyes (64 patients) undergoing laser in situ keratomileusis (LASIK) without corneal ectasia after 24 months of follow-up and 55 case eyes with unilateral keratoconus from a database (BCVA of 1.0, KISA index <60%). All eyes were matched in four groups of central corneal thickness (CCT): group 1, <500 microm; group 2, 500 to 539 microm; group 3, 540 to 579 microm; and group 4 >580 microm. Corneal hysteresis (CH), the corneal resistance factor (CRF), the air pressure curve, and the infrared signal were compared between FFKc and normal eyes in each group. RESULTS: The mean CH was 9.1 +/- 1.8 mm Hg for FFKc and 10.3 +/- 1.9 mm Hg for control eyes (P < 0.001), and the mean CRF was 9.2 +/- 1.8 and 11.1 +/- 2 mm Hg (P < 0.001), respectively. Sensitivity in each group was as follows: group 1, CH < 9.5 mm Hg (91%) and CRF < 9.5 mm Hg (81%); group 2, CH < 10.5 mm Hg (91%) and CRF < 10 mm Hg (87%); group 3, CH < 11.5 mm Hg (79%) and CRF < 11 mm Hg (74%); group 4 had two cases of FFKc, and the difference was not significant. Air pressure levels at inward and outward applanation and the maximum air pressure level were significantly lower and shorter in time in FFKc (P < 0.001), whereas the shape of the infrared signal was more variable. CONCLUSIONS: The ORA provides additional information in the screening of FFKc, with an accurate analysis of the corneal biomechanical properties according to CCT, air pressure, and infrared curves.
Authors:
Cedric Schweitzer; Cynthia J Roberts; Ashraf M Mahmoud; Joseph Colin; Sylvie Maurice-Tison; Julien Kerautret
Related Documents :
16564045 - Predictability and limitations of non-invasive murine tonometry: comparison of two devi...
20507195 - Pigment dispersion with elevation of intraocular pressure after bilateral phacoemulsifi...
15181965 - Clinical experience in the management of neovascular glaucoma.
18670465 - Changes in visual function after intraocular pressure reduction using antiglaucoma medi...
17558845 - Did edgar degas have an inherited retinal degeneration?
12213265 - Comparison of the effects of modafinil and sleep deprivation on sleep and cortical eeg ...
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-11-11
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  51     ISSN:  1552-5783     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-03     Completed Date:  2010-05-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2403-10     Citation Subset:  IM    
Affiliation:
National Reference Center for Keratoconus, Department of Ophthalmology, University Hospital Pellegrin, Bordeaux, France. cedric.schweitzer@yahoo.fr
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Biomechanics
Compliance
Cornea / pathology*
Diagnostic Techniques, Ophthalmological*
Dilatation, Pathologic
Female
Follow-Up Studies
Humans
Keratoconus / diagnosis*,  surgery
Keratomileusis, Laser In Situ
Male
ROC Curve
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Noninvasive visualization and analysis of parafoveal capillaries in humans.
Next Document:  LONG-TERM DIETARY OMEGA-3 DEFICIENCY EXACERBATES ROD PHOTORECEPTOR DYSFUNCTION IN THE DIABETIC RAT.