Document Detail


Screening for fetal risk with urinary oestrogen: creatinine ratio at 34 weeks.
MedLine Citation:
PMID:  7387938     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The urinary oestrogen:creatinine (O/C) ratio was measured in first morning specimens of 261 women at 34 weeks gestation to assess prospectively its potential in predicting fetal complications. Forty-two patients (16.1 per cent) had low O/C ratios. All three stillbirths in the series occurred in this group and the incidences of fetal growth retardation and fetal distress in labour were also significantly increased. These complications were unusual when the O/C ratio was high. The O/C ratio at 34 weeks reflected fetal well-being more accurately than clinical examination or blood pressure measurement. The mean O/C ratios of cigarette smokers non-smokers were similar, although smokers were delivered of lighter babies. Measurement of the urinary O/C ratio is simple and inexpensive. Used as a screening test at 34 weeks it appears to provide an early and fairly reliable indication of reduced placental function.
Authors:
C O'Herlihy; R H Martin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  87     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1980 May 
Date Detail:
Created Date:  1980-09-28     Completed Date:  1980-09-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  388-92     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Creatinine / urine*
Estrogens / urine*
Female
Fetal Death / diagnosis
Fetal Diseases / diagnosis
Humans
Placenta Diseases / diagnosis*
Placental Insufficiency / diagnosis*
Pregnancy
Pregnancy Complications / diagnosis*
Pregnancy Trimester, Third
Prenatal Diagnosis*
Smoking
Chemical
Reg. No./Substance:
0/Estrogens; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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