| Screening extracts of Euphorbia garuana N.E.Br. for in-vitro cytotoxicity. | |
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MedLine Citation:
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PMID: 2854369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two biological assays utilising in-vitro uptake of 3H-thymidine into TLX/5 lymphoma and rat basophilic leukaemia cells have been used for rapid detection and subsequent isolation of active compounds from the latex of Euphorbia garuana (Euphorbiaceae). Two potent esters were characterized from the latex of E. garuana reportedly used in traditional medicine for the treatment of certain forms of cancer. |
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Authors:
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K A Abo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: African journal of medicine and medical sciences Volume: 17 ISSN: 0309-3913 ISO Abbreviation: Afr J Med Med Sci Publication Date: 1988 Dec |
Date Detail:
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Created Date: 1989-05-26 Completed Date: 1989-05-26 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7801013 Medline TA: Afr J Med Med Sci Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 227-30 Citation Subset: IM |
Affiliation:
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Department of Pharmacognosy, Faculty of Pharmacy, College of Medicine, University of Ibadan, Nigeria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antineoplastic Agents, Phytogenic / analysis* Cell Survival Chemical Phenomena Chemistry Diterpenes / analysis, isolation & purification* Female Leukemia, Basophilic, Acute / pathology Lymphoma / pathology Mice Mice, Inbred CBA Plant Extracts / analysis* Plants, Medicinal / analysis Rats Thymidine / metabolism Tumor Cells, Cultured |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents, Phytogenic; 0/Diterpenes; 0/Plant Extracts; 135467-87-7/7-benzoylingol-3,8,12-triacetate; 50-89-5/Thymidine; 51906-02-6/ingol-3,7,8,12-tetraacetate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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