| Screening for congenital hypothyroidism in the Islamic Republic of Iran: strategies, obstacles and future perspectives. | |
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MedLine Citation:
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PMID: 15603028 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The operational feasibility of a congenital hypothyroidism (CH) screening programme was assessed. Cord blood spot specimens were collected at seven Teheran hospitals and within the Damavand District health network. Cord thyroid-stimulating hormone (TSH) levels > or = 20 mU/L were recalled and levothyroxine (L-T4) therapy was started immediately after diagnosis of CH. Of 20,107 acceptable specimens, 22 neonates had CH (1:914 births). The recall rate was 1.3%. Screening coverage was 90% of live births. Of all cord samples, only 0.2% were unacceptable either because of delay in transportation or improper specimen collection. Median ages at the time of diagnosis and starting treatment were 12 and 8 days respectively. Screening for CH is feasible and a national screening programme is a necessity. |
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Authors:
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A Ordookhani; P Mirmiran; R Hajipour; M Hedayati; F Azizi |
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Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Eastern Mediterranean health journal = La revue de santé de la Méditerranée orientale = al-Majallah al-ṣiḥḥīyah li-sharq al-mutawassiṭ Volume: 8 ISSN: 1020-3397 ISO Abbreviation: East. Mediterr. Health J. Publication Date: 2002 Jul-Sep |
Date Detail:
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Created Date: 2004-12-16 Completed Date: 2005-01-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9608387 Medline TA: East Mediterr Health J Country: Egypt |
Other Details:
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Languages: eng Pagination: 480-9 Citation Subset: IM |
Affiliation:
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Endocrine and Metabolism Research Centre, Shaheed Beheshti University of Medical Sciences, Teheran, Islamic Republic of Iran. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Blood Specimen Collection / methods, standards Congenital Hypothyroidism* Decision Trees Feasibility Studies Fetal Blood / chemistry Forecasting Health Services Research Hospitals, Urban Humans Hypothyroidism / blood, diagnosis*, drug therapy, epidemiology Incidence Infant, Newborn Iran / epidemiology National Health Programs Needs Assessment Neonatal Screening / organization & administration* Organizational Objectives Population Surveillance Program Evaluation Quality Indicators, Health Care Thyrotropin / blood Time Factors |
| Chemical | |
Reg. No./Substance:
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9002-71-5/Thyrotropin |
| Comments/Corrections | |
Erratum In:
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East Mediterr Health J. 2004 Jul-Sep;10(4-5):632 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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