Document Detail

Screening for autistic spectrum disorder at the 18-month developmental assessment: a population-based study.
MedLine Citation:
PMID:  17955715     Owner:  NLM     Status:  MEDLINE    
The objectives of this study were to assess the feasibility of administering the CHecklist for Autism in Toddlers (CHAT) at the 18-month developmental check, estimate the prevalence of screening positive for autism at the first and second administrations of the CHAT and estimate the prevalence of diagnosed cases of autism. A cross-sectional study design was utilised and data was collected at child developmental screening clinics in counties Cork and Kerry. The sample group consisted of infants attending the routine 18-month developmental assessment, who were broadly representative of infants in the catchment area. The main outcome measure was a medium or high-risk score following two administrations of the CHAT screening instrument and a positive diagnosis of autism after clinical assessment. The CHAT was administered to 2117 infants (79% of those approached) of whom 29 were scored at medium or high risk at first screening, resulting in a prevalence rate of 137 per 10,000 (95% CI: 87-187). A total of 7 of the 29 first screen positive infants were positive (medium or high risk) at second screening, 12 were low risk and 10 parents refused to participate. On subsequent clinical assessment of the 7 infants screening positive on first and second assessment and assessment of 5 of the 10 infants whose parents declined second screening, 7 children received a diagnosis of autism. Thus the overall prevalence of clinically diagnosed autism following this screening exercise was 33.1 per 10,000 (95% CI: 13.3 to 68.0). The CHAT instrument is a useful tool to help identify childhood autism among infants. Routine use of this instrument at 18-month developmental assessment merits consideration.
A VanDenHeuvel; M Fitzgerald; B Greiner; I J Perry
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Irish medical journal     Volume:  100     ISSN:  0332-3102     ISO Abbreviation:  Ir Med J     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-10-24     Completed Date:  2007-12-06     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0430275     Medline TA:  Ir Med J     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  565-7     Citation Subset:  IM    
Department of Epidemiology & Public Health, University College Cork.
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MeSH Terms
Age Factors
Autistic Disorder / diagnosis*
Cross-Sectional Studies
Developmental Disabilities / diagnosis
Feasibility Studies
Infant Care*
Mass Screening / methods*
Psychiatric Status Rating Scales / standards
Public Health Nursing
Risk Assessment
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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