| Screening for aortic root dilation in marfan syndrome using the ratio of the aortic root to descending aortic diameters in children. | |
| | |
MedLine Citation:
|
PMID: 19647408 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The aim of this study was to develop a simpler echocardiographic screening tool for aortic root dilation in pediatric patients with Marfan syndrome. Aortic root dilation represents the most common cause of morbidity and mortality in patients with Marfan syndrome. It is traditionally defined by nomograms, relating aortic root dimensions to height or body surface area. In this study, the descending aorta (DAo) was used as an internal reference, thereby eliminating the need for nomograms when screening for aortic root dilation. METHODS: The diameters of the aortic root at the sinus of Valsalva and the DAo were measured in 35 patients with Marfan syndrome and 52 normal controls in the parasternal long-axis echocardiographic view. The root/DAo ratio was calculated. RESULTS: A root/DAo ratio > or = 2 provided optimal sensitivity for root dilation (100%), whereas a root/DAo ratio > or = 2.3 provided optimal specificity (100%). CONCLUSION: The root/DAo ratio provides a simple, rapid, and valuable screening test for aortic root dilation, independent of nomograms and body size. |
| | |
Authors:
|
Mariska S Kemna; Daniel J Murphy; Norman H Silverman |
Related Documents
:
|
22390118 - Churg-strauss syndrome presenting with conjunctival and eyelid masses: a case report. 1970928 - Gastric argyrophil carcinoidosis in patients with zollinger-ellison syndrome due to typ... 20066398 - Urinary incontinence should be added to the manifestation in women with marfan syndrome. 1984998 - Helicobacter pylori and zollinger-ellison syndrome. 17827948 - Almost all irritable bowel syndromes are post-infectious and respond to probiotics: con... 11841958 - Delayed puberty. |
Publication Detail:
|
Type: Journal Article Date: 2009-07-31 |
Journal Detail:
|
Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 22 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2009 Oct |
Date Detail:
|
Created Date: 2009-10-05 Completed Date: 2010-01-04 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
|
Languages: eng Pagination: 1109-13 Citation Subset: IM |
Affiliation:
|
Division of Pediatric Cardiology, Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, Washington 98105, USA. mariska.kemna@seattlechildrens.org |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Algorithms* Aortic Diseases / ultrasonography* Child Echocardiography / methods* Female Humans Image Enhancement / methods Image Interpretation, Computer-Assisted / methods* Male Marfan Syndrome / ultrasonography* Mass Screening / methods* Pattern Recognition, Automated / methods* Reproducibility of Results Sensitivity and Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Transplantation of bone marrow-derived stem cells improves myocardial diastolic function: strain rat...
Next Document: Assessment of intraventricular mechanical dyssynchrony and prediction of response to cardiac resynch...