Document Detail


Screening for antenatal depression with the Edinburgh Depression Scale.
MedLine Citation:
PMID:  19845492     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study aimed to evaluate how precise the Edinburgh Depression Scale (EDS) is in screening for major depressive disorder (MDD) during different periods of pregnancy. A random sample of 230 pregnant women was interviewed in the first, second, and third trimesters of pregnancy using the EDS and not-patient version of the Structured Clinical Interview for DSM-III-R (SCID-NP). We evaluated test-retest reliability of the EDS; area under the ROC curve (AUC), sensitivity, specificity, and positive predictive value (PPV) of the EDS against the SCID-NP diagnoses in the first, second, and third trimesters of pregnancy. Test-retest reliability of the EDS was 0.81 (p < 0.001). An optimal cutoff score of the EDS for screening current SCID-NP diagnosis of MDD was 12 and higher in the first trimester of pregnancy (AUC 0.94, sensitivity 92%, specificity 95%, and PPV 52%) and 11 and higher in the second and third trimesters of pregnancy (AUC 0.96 and 0.90, respectively; sensitivity 100% and 88%, respectively; specificity 92% and 92%, respectively; PPV 25% and 29%, respectively). The EPDS is a reliable instrument for repeated evaluations of depressive symptoms during pregnancy. It has a good sensitivity and specificity for detecting antenatal MDD with optimal cutoff of 11/12 or higher.
Authors:
Adomas Bunevicius; Laima Kusminskas; Victor J Pop; Cort A Pedersen; Robertas Bunevicius
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of psychosomatic obstetrics and gynaecology     Volume:  30     ISSN:  1743-8942     ISO Abbreviation:  J Psychosom Obstet Gynaecol     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-20     Completed Date:  2010-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308648     Medline TA:  J Psychosom Obstet Gynaecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  238-43     Citation Subset:  IM    
Affiliation:
Institute of Physiology and Rehabilitation, Kaunas University of Medicine, LT - 00135 Palanga, Lithuania. a.bunevicius@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Area Under Curve
Depressive Disorder / diagnosis*
Female
Humans
Pregnancy
Pregnancy Complications / diagnosis*,  psychology
Psychiatric Status Rating Scales
ROC Curve
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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