Document Detail


Screening for Staphylococcus aureus carriage in pregnancy: usefulness of novel sampling and culture strategies.
MedLine Citation:
PMID:  19716114     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study was to determine the most sensitive strategy for the detection of Staphylococcus aureus among pregnant women and newborn infants. STUDY DESIGN: We obtained cultures for S aureus from 5 body sites of women at 35-37 weeks' gestation. We obtained cultures from their newborn infants before hospital discharge. RESULTS: Of 209 women who were screened, 29% of the women had at least 1 culture that was positive for S aureus; 5% of infants were S aureus carriers. The sensitivities of each site for S aureus detection were 52% nares, 50% throat, 13% rectum, 8% vagina, and 10% skin. The most sensitive combination of 2 sites was nares and throat (88%). Perinatal transmission of S aureus occurred in 4 women. Maternal methicillin-resistant S aureus carriage rate was 1%. Two infants carried the USA300 methicillin-resistant S aureus. CONCLUSION: Screening single body sites is insensitive for the detection of S aureus carriage in pregnancy. Sampling nares and throat is essential to the identification of S aureus carriers.
Authors:
Janet I Andrews; Diedre K Fleener; Shawn A Messer; Jennifer S Kroeger; Daniel J Diekema
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Publication Detail:
Type:  Journal Article     Date:  2009-08-28
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  201     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-30     Completed Date:  2009-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  396.e1-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Iowa College of Medicine, Iowa City, IA, USA.
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MeSH Terms
Descriptor/Qualifier:
Carrier State*
Electrophoresis, Gel, Pulsed-Field
Female
Humans
Infant, Newborn
Nose / microbiology
Pharynx / microbiology
Pregnancy
Pregnancy Complications, Infectious / diagnosis*
Prospective Studies
Sensitivity and Specificity
Staphylococcal Infections / diagnosis*
Staphylococcus aureus / isolation & purification

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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