| Screening, diagnosing and prevention of fetal alcohol syndrome: is this syndrome treatable? | |
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MedLine Citation:
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PMID: 20551645 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Prenatal alcohol exposure can lead to a wide range of adverse effects on a developing fetus. As a whole, these teratogenic outcomes are generally known as fetal alcohol spectrum disorders, the most severe of which is fetal alcohol syndrome (FAS). Clinically, children diagnosed with FAS vary greatly in their presentation of symptoms, likely due to the amount of alcohol and timing of exposure, as well as maternal and genetic influences. All these factors play a role in determining the mechanisms through which alcohol damages a developing brain, the details of which are still largely unknown. However, continuing research and recent developments have provided promising results that may lead to screening mechanisms and treatment therapies for children with FAS. Here we review the teratogenic effects of alcohol, strategies for detecting maternal alcohol consumption, identification of fetal biological markers, and prevention methods for FAS. |
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Authors:
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Sahar Ismail; Stephanie Buckley; Ross Budacki; Ahmad Jabbar; G Ian Gallicano |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-06-16 |
Journal Detail:
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Title: Developmental neuroscience Volume: 32 ISSN: 1421-9859 ISO Abbreviation: Dev. Neurosci. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-07 Completed Date: 2010-10-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7809375 Medline TA: Dev Neurosci Country: Switzerland |
Other Details:
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Languages: eng Pagination: 91-100 Citation Subset: IM |
Copyright Information:
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Copyright 2010 S. Karger AG, Basel. |
Affiliation:
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Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, D.C. 20057, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alcohol Drinking
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adverse effects* Biological Markers / metabolism Child Ethanol / adverse effects* Family Female Fetal Alcohol Syndrome / diagnosis*, pathology, physiopathology, prevention & control* Humans Pregnancy Prenatal Exposure Delayed Effects* / chemically induced, prevention & control Risk Factors Teratogens |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Teratogens; 64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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