Document Detail


Scrapie and transmissible mink encephalopathy: search for infectious nucleic acid.
MedLine Citation:
PMID:  4207527     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Brain preparations from animals with scrapie or transmissible mink encephalopathy were phenol extracted and examined for the presence of pathogenic nucleic acid. Animals inoculated with various extracts remained healthy, and analysis on 2.6 to 5% polyacrylamide gels failed to detect a difference in extractable RNA species between infected and normal mink brain.
Authors:
R F Marsh; J S Semancik; K C Medappa; R P Hanson; R R Rueckert
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of virology     Volume:  13     ISSN:  0022-538X     ISO Abbreviation:  J. Virol.     Publication Date:  1974 May 
Date Detail:
Created Date:  1974-06-25     Completed Date:  1974-06-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0113724     Medline TA:  J Virol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  993-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain Chemistry*
Electrophoresis, Polyacrylamide Gel
Mice
Mink
Prions
RNA, Viral / analysis*
Scrapie / microbiology*
Sheep
Slow Virus Diseases / microbiology*
Viruses, Unclassified*
Chemical
Reg. No./Substance:
0/Prions; 0/RNA, Viral
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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