Document Detail


Scrapie associated fibrils in the diagnosis of scrapie in sheep.
MedLine Citation:
PMID:  3604027     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Previous research has consistently demonstrated by electron microscopy the presence of scrapie associated fibrils in brain extracts prepared from mice and hamsters with clinical signs of experimental scrapie. In the present study similar fibrils were seen in all the brain extracts prepared from 11 Cheviot or Suffolk sheep with natural or experimental scrapie that had been diagnosed clinically and confirmed neuropathologically. They were not found in the brain extracts of nine sheep that did not have scrapie and which included four that had been injected with infected material but did not develop the disease. The presence of such fibrils can therefore be used as an additional diagnostic criterion for natural scrapie in sheep.
Authors:
P H Gibson; R A Somerville; H Fraser; J D Foster; R H Kimberlin
Related Documents :
22984867 - Altered theta coupling between medial entorhinal cortex and dentate gyrus in temporal l...
19601817 - Blood-brain barrier transport of drugs for the treatment of brain diseases.
21061157 - Brain pericytes: emerging concepts and functional roles in brain homeostasis.
5789807 - Glycol metabolites of noradrenaline in brain tissue.
23640807 - Brain-derived neurotrophic factor/trkb signaling regulates daily astroglial plasticity ...
681987 - Generation of scratching. i. activity of spinal interneurons during scratching.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Veterinary record     Volume:  120     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-08-10     Completed Date:  1987-08-10     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  125-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Brain / ultrastructure*
Cerebral Cortex / ultrastructure
Microscopy, Electron
Scrapie / diagnosis*,  pathology
Sheep

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Xylazine and ketamine anaesthesia in the dromedary camel under field conditions.
Next Document:  Protection of cattle against heartwater in Botswana: comparative efficacy of different methods again...