| Sclerosing treatment of lymphangiomas with OK-432. | |
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MedLine Citation:
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PMID: 10735841 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Over a period of seven years, 15 patients (aged from birth to 15 years; median 22 months) with lymphangioma were treated with OK-432; they received a mean of three injections each. Ten received OK-432 as first line treatment; five were treated after surgery (three had a residual lymphangioma after incomplete removal and two had a late recurrence). OK-432 proved to be effective for primitive as well as for residual and recurrent lymphangioma. Seven cases were macrocystic; complete regression was obtained in all. Five cases were microcystic: two had more than 50% regression, and three less than 50%. Three cases were mixed, with both large and microscopic cysts: one had more than 50% regression, and two less than 50%. These last two cases underwent surgery after the sclerosing treatment. The results obtained were excellent in 100% of macrocystic cases; a shrinkage in size was obtained in all microcystic cases. OK-432 is therefore proposed as a first line option for treatment of lymphangiomas. |
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Authors:
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C Luzzatto; P Midrio; Z Tchaprassian; M Guglielmi |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of disease in childhood Volume: 82 ISSN: 1468-2044 ISO Abbreviation: Arch. Dis. Child. Publication Date: 2000 Apr |
Date Detail:
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Created Date: 2000-04-12 Completed Date: 2000-04-12 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0372434 Medline TA: Arch Dis Child Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 316-8 Citation Subset: AIM; IM |
Affiliation:
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Divisione di Chirurgia Pediatrica, Via Giustiniani 3, 35128 Padova, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Antineoplastic Agents / therapeutic use Child Child, Preschool Head and Neck Neoplasms / therapy* Humans Infant Infant, Newborn Lymphangioma / radiography, therapy* Picibanil / therapeutic use Sclerotherapy / methods* |
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Reg. No./Substance:
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0/Antineoplastic Agents; 39325-01-4/Picibanil |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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