| Sclerosing cholangitis with neonatal onset. | |
| | |
MedLine Citation:
|
PMID: 3612394 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Sclerosing cholangitis is characterized by irregular narrowing of extrahepatic or intrahepatic bile ducts, and in adults is defined mainly by radiologic findings. We describe eight children with cholestasis from the first week of life, followed by early cirrhosis and portal hypertension. Histologic examination of the liver showed absence of interlobular bile ducts in the early cholestatic phase in two patients and biliary cirrhosis later in all patients. Radiologic examination by percutaneous cholecystography under ultrasound guidance, carried out at age 8 months to 9 years, disclosed abnormal intrahepatic bile ducts with rarefaction of segmental branches, stenosis, and focal dilation. The extrahepatic ducts were involved in six patients. No intestinal disease has been found in these patients. |
| | |
Authors:
|
O Amedee-Manesme; O Bernard; F Brunelle; M Hadchouel; C Polonovski; J J Baudon; P Beguet; D Alagille |
Related Documents
:
|
20026714 - Sialographic findings in wharton duct evagination. 3142924 - Sonography of normal lower ureters. 6424434 - Biochemical and morphological investigations of the toxicity of a capmul preparation an... 15011834 - Scintigraphic sign of functional biliary obstruction is pathognomic for sphincter of od... 19474574 - Incidence of spontaneous echocontrast, 'sludge' and thrombi before cardioversion in pat... 21048624 - Adiponectin and infarction size in subjects with and without cerebrovascular disease. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Journal of pediatrics Volume: 111 ISSN: 0022-3476 ISO Abbreviation: J. Pediatr. Publication Date: 1987 Aug |
Date Detail:
|
Created Date: 1987-09-10 Completed Date: 1987-09-10 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 225-9 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bile Ducts
/
pathology* Child Child, Preschool Cholangiography Cholangitis / diagnosis*, metabolism, pathology Female Humans Infant Infant, Newborn Liver / pathology Liver Cirrhosis / pathology Male Sclerosis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bioavailability of dietary urea nitrogen in the infant.
Next Document: Vascular pathogenesis of unilateral craniofacial defects.