| Scleromyxedema myopathy: case report and review of the literature. | |
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MedLine Citation:
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PMID: 3056423 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a patient who had scleromyxedema associated with proximal myopathy. The histopathologic and electron microscopic features are presented. In addition, we review the clinical and pathologic features of all 9 previously reported patients with documented scleromyxedema and myopathy. Proximal (pharyngeal) or distal dysphagia (7 of 7 patients), elevated creatine kinase (5 of 8), elevated aldolase (3 of 3), and electromyographically demonstrated myopathy (7 of 7) were usual features. Four patients had muscle biopsies that showed myofibril vacuolar changes, but inflammation was infrequent (2 cases). Our patient responded to oral prednisone and weekly intravenous methotrexate with improvement of the erythroderma, papular rash, and muscle strength. |
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Authors:
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D J Helfrich; E R Walker; A J Martinez; T A Medsger |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Arthritis and rheumatism Volume: 31 ISSN: 0004-3591 ISO Abbreviation: Arthritis Rheum. Publication Date: 1988 Nov |
Date Detail:
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Created Date: 1988-12-16 Completed Date: 1988-12-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370605 Medline TA: Arthritis Rheum Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1437-41 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, University of Pittsburgh School of Medicine, Pennsylvania. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arm Biopsy Deglutition Disorders / complications Electromyography Face Female Humans Middle Aged Muscles / pathology, ultrastructure Muscular Diseases / complications*, pathology, physiopathology Skin Diseases / complications*, pathology, physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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