Document Detail

Scleroderma (systemic sclerosis) among Nigerians.
MedLine Citation:
PMID:  19437086     Owner:  NLM     Status:  MEDLINE    
Scleroderma and other connective tissue diseases have rarely been reported among Africans. The objective of this paper is to have a retrospective study of the clinical and investigative characteristics of scleroderma patients seen in a rheumatology clinic. This was done in a private practice rheumatology clinic in Lagos, Nigeria. Patients were identified using the American College of Rheumatology criteria for diagnosis of scleroderma. A total of 14 cases of scleroderma are reported. Most of the patients were females and diffuse scleroderma was more frequently seen. Arthritis and reflux esophagitis were the most common nondermatological presentation while Raynaud's phenomenon and dysphagia were the least seen. Restrictive pattern of lung function tests were seen in most of those tested and pulmonary fibrosis was seen in some cases. Antinuclear antibodies were the commonest serological findings with the speckled staining pattern in most cases. Treatments were with standard medications. Scleroderma among Nigerians is rare as elsewhere and there are certain common characteristics as seen elsewhere as well as certain differences.
O O Adelowo; S Oguntona
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-05-13
Journal Detail:
Title:  Clinical rheumatology     Volume:  28     ISSN:  1434-9949     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-05     Completed Date:  2009-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1121-5     Citation Subset:  IM    
Rheumatology Unit, Department of Medicine, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria.
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MeSH Terms
African Continental Ancestry Group*
Hyperpigmentation / ethnology,  pathology
Hypopigmentation / ethnology,  pathology
Middle Aged
Pulmonary Fibrosis / ethnology,  radiography
Retrospective Studies
Scleroderma, Systemic / ethnology*,  pathology*
Skin / pathology*

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