Document Detail


Sclerodactyly in a patient with mycosis fungoides.
MedLine Citation:
PMID:  3970626     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 44-year-old man had mycosis fungoides and generalized plaque disease involving 80% of his skin surface with diffuse lymphadenopathy and alopecia of the scalp and groin. In addition, distal to the wrist, there were sclerodermatous changes involving the skin of the hands with associated sclerodactyly of all digits with loss of normal palmar creases. There were no subungual telangiectasis or digital ulcers. The changes in the hand that occurred in this case, no doubt arose as a result of the patient's neoplasm. Abnormalities of collagen biosynthesis and degradation probably occur with mycosis fungoides as a result of the extensive infiltration of the epidermis and dermis with malignant cells. To our knowledge, the association of sclerodactyly with mycosis fungoides has not been previously reported.
Authors:
N Wei; K A Foon
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of internal medicine     Volume:  145     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1985 Jan 
Date Detail:
Created Date:  1985-02-27     Completed Date:  1985-02-27     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  139-40     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Hand* / pathology
Humans
Male
Mycosis Fungoides / complications*,  pathology
Scleroderma, Systemic / complications*,  pathology
Skin Neoplasms / complications*,  pathology
Grant Support
ID/Acronym/Agency:
N01-CO-23910/CO/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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